Update/Activate iPhone anti-phishing feature

In order for Safari's anti-phishing database to update, there are a few particular steps that need to be followed.After updating the phone to the OS 3.1 update, users need to do the following:

1.Launch the Safari web browser.
2.Connect to a Wi-Fi network.
3.Charge the iPhone with the screen off.

This will update the phishing sites database and you'll be warned if you reach any such website with your safari browser on iPhone.

Anti-phishing feature is not available on any other mobile phone as far as I know.

Sarbjit Singh
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Postop endophthalmitis rate comparable for 20- and 25-gauge vitrectomy

This retrospective series included 1,948 cases of sutured 20-gauge pars plana vitrectomy (PPV) and 1,424 cases of sutureless 25-gauge PPV. At one-year follow-up, endothalmitis rates were similar. The authors believe their anti-infection protocol – povidone–iodine applied to the ocular surface and fornices before surgery. Injections of both subconjunctival antibiotic over each sclerotomy site and steroids after surgery – may have reduced the endophthalmitis risk of 25-gauge surgery. Ophthalmology, July 2009


Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments

Low-dose fibrinolytic therapy may improve vision in patients with acute central retinal vein occlusion

Researchers randomized 53 patients with central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) to undergo either thrombolysis with 50 mg of recombinant tissue plasminogen activator (rt-PA) or hemodilution within 11 days of symptom onset. They were followed for one year. Among CRVO patients, median BCVA was 20/60 in the rt-PA group vs. 20/400 in the hemodilution group. Among BRVO patients, there was a tendency for better vision in the rt-PA group, but the difference did not reach statistical significance, possibly due to the smaller subject pool. Retina, July/August 2009

Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments

Bilateral, simultaneous intravitreal injections appear well tolerated

This retrospective study evaluated 35 patients who received a mean of 5.9 injections over a one-year period. Some received Avastin or Lucentis alone, others Avastin in combination with triamcinolone or dexamethasone. A separate povidone-iodine preparation, speculum, needle, and syringe were used for each eye. Outcomes were positive and no patient requested alternating unilateral injections, after receiving bilateral injections. American Journal of Ophthalmology, July 2009

Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments

Avastin prior to vitrectomy for severe diabetic retinopathy appears beneficial

Researchers alternatively assigned 39 consecutive patients (41 eyes) undergoing primary pars plana vitrectomy with silicone oil tamponade to receive one Avastin injection one week before surgery or no pretreatment. In the Avastin group, intra- and postoperative bleeding was significantly less, as was blood reabsorption time (11.1 vs. 34.8 days). BCVA improvement was significantly greater. However, subretinal bleeding was significantly more common in the Avastin group (nine cases vs. one). Retina, June 2009

Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments (1)

Angle-supported phakic IOL shows promising one-year results

AcrySof phakic angle-supported IOL was implanted in 190 eyes (190 subjects) with moderate to high myopia in this phase three, nonrandomized, open-label, prospective study. One-year postoperative UCVA was 20/20 or better in 57.8 percent of subjects and 20/40 or better in 99.4 percent. All subjects obtained BSCVA of 20/32 or better, and 85.7 percent reached 20/20 or better. Mean central endothelial density decreased 4.77 percent (15 percent experienced 10 percent or more loss). No pupil ovalization, pupillary block or retinal detachment occurred. Ophthalmology, July 2009

Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments (1)

Oral famciclovir appears a good treatment option for acute retinal necrosis

Researchers assigned 10 patients (10 eyes) undergoing pars plana vitrectomy to take three 500-mg doses the day before surgery and another dose one hour before surgery. Analysis of vitreous samples taken during surgery showed potentially therapeutic concentrations of the active metabolite penciclovir. Though not necessarily superior to oral valacyclovir or intravenous acyclovir, famciclovir may be a reasonable choice given its favorable pharmacokinetic profile and lower potential toxicity, the authors concluded. American Journal of Ophthalmology, July 2009

Dr Sarbjit Singh
EYE FOR EXCELLENCE
Comments

VEGF Trap-Eye shows promising early results in diabetic macular edema

Researchers treated five patients with a single intravitreal injection of 4.0 mg of VEGF Trap-Eye, and followed them for six weeks. No ocular toxicity was observed. At six weeks, four of the five patients showed improvement in foveal thickness (median 31 percent reduction from baseline) and improvement in BCVA (median improvement of three letters). Compared with Lucentis, VEGF Trap-Eye has a longer half-life after intraocular injection, a higher binding affinity to VEGF-A, and it binds to other members of the VEGF family, including placental growth. British Journal of Ophthalmology, February 2009

Dr. Sarbjit Singh
EYE FOR EXCELLENCE
Comments

PCR testing appears a useful adjunct in diagnosis of infectious posterior uveitis

This retrospective analysis examined the results of PCR testing on 133 patients presenting at a single institution with possible chorioretinitis. The authors used a commercial reference laboratory for testing a total of 433 PCR assays on acquired aqueous and vitreous samples. PCR testing of aqueous humor was found to be a safe, easily performed first-line diagnostic procedure that is useful as an adjunct to careful history and clinical examination. In most cases, vitreous sampling was not required, and PCR reaction alone without antibody testing resulted in a large percentage of confirmed diagnoses. Cases with vascular or optic nerve inflammation, extensive retinitis, or immunocompromise may benefit from adjunctive anterior chamber PCR testing, especially if the testing is carried out relatively early in the disease course. American Journal of Ophthalmology, January 2009

Dr. Sarbjit Singh
EYE FOR EXCELLENCE
Comments

OCT shows oblique incisions provide adequate wound closure even one day after surgery

Researchers prospectively evaluated 14 consecutive patients who underwent 23-gauge sutureless vitrectomy. All incisions were oblique (beveled or angled) tunneled incisions parallel to the limbus. Visante OCT images showed all incisions were securely closed on day one and day eight postop. American Journal of Ophthalmology, January 2009

Dr. Sarbjit Singh
EYE FOR EXCELLENCE
Comments