This retrospective analysis examined the results of PCR testing on 133 patients presenting at a single institution with possible chorioretinitis. The authors used a commercial reference laboratory for testing a total of 433 PCR assays on acquired aqueous and vitreous samples. PCR testing of aqueous humor was found to be a safe, easily performed first-line diagnostic procedure that is useful as an adjunct to careful history and clinical examination. In most cases, vitreous sampling was not required, and PCR reaction alone without antibody testing resulted in a large percentage of confirmed diagnoses. Cases with vascular or optic nerve inflammation, extensive retinitis, or immunocompromise may benefit from adjunctive anterior chamber PCR testing, especially if the testing is carried out relatively early in the disease course. American Journal of Ophthalmology, January 2009

Dr. Sarbjit Singh
EYE FOR EXCELLENCE

AsianOphthalmology